Burkholderia Comparative Genomics

1. Does chromosome position affect gene evolutionary rate?

2. How does gene family presence define species groups? What gene families define the Bcc, Bps, and Burk complexes in general, and what gene families define different species groups? Are these gain/losses driven by HGT?

3. Love the one you’re with: What gene families span Burkholderia and Pseudomonas in spite of evolutionary distance?

4. Does gene family size better determine Burkholderia genome diversity than ortholog presence/absence?

5. GenomeHistory: Among young gene duplicates in prokaryotic genomes, where are they located in the genome, and what COG groups are preferentially involved? Are certain gene types more prone to duplication within the genome as opposed to gain by HGT?